مرض داريه الموضعي: ماذا تفعل عندما تفشل الرعاية الداعمة في تحسين الحكة وتهيج الجلد

DOI: 10.25259/IJDVL_963_19

For localized and resistant skin lesions, physical therapies including surgical excision, dermabrasion and CO2 laser ablation were the first line choices.

In 16 patients with a mean age of 43 (half of which were males), a formulation of 0.05% applied twice daily for 3 months was used.

Formulations of 0.1% isotretinoin were used by 3 patients for 1 to 3 months, with complete resolution of symptoms in 1 patient.

A total of 4 women with a mean age of 45 years used Tazarotene 0.05% and 0.1% daily with complete resolution of their symptoms.

Adapalene gel, a synthetic retinoid, was used in a total of 3 patients at a concentration of 0.1% daily for 2 months; all showed marked improvement with no side effects.

They have mostly been used in association with retinoids to reduce irritation.

Of those, 6 (35%) patients showed complete resolution of symptoms with only 1 patient experiencing a relapse following a month of treatment discontinuation.