علاج داء الكيسات العصبية تحت العنكبوتية مع أكياس في الصهاريج القاعدية أو شقوق سيلفيوس

References

DOI: 10.1093/cid/cix1084

• When located in the basal cisterns of the subarachnoid space or Sylvian fissure, the manifestations can be severe.
• We recommend that patients with subarachnoid cysts be treated with antiparasitic drugs (strong, low).
• We recommend anti-inflammatory therapy (such as high-dose corticosteroids) for subarachnoid NCC initiated prior to antiparasitic drugs (strong, moderate).
• We recommend that patients with hydrocephalus from subarachnoid NCC be treated with shunt surgery in addition to medical therapy (strong, low).
• We suggest that methotrexate be considered as a steroid-sparing agent in patients requiring prolonged courses of anti-inflammatory therapy (weak, low).
• Options to improve responses include prolonged administration of albendazole (15 mg/kg/d for months) or combination therapy with albendazole (15 mg/kg/d plus praziquantel 50 mg/kg/d).
• We suggest that antiparasitic therapy be continued until there is radiologic resolution of viable cysticerci on MRI and resolution of other evidence of cysticerci (weak, low).