يتناول هذا البروتوكول إدارة آفات الساركويد الجلدي النوعية (الحبيبية) ذات الأهمية التجميلية والمحدودة العدد — وهو مظهر يؤثر فيه توزع الآفات ومدى ظهورها بشكل مباشر على نهج العلاج.
If the patient has very few localized lesions, they may respond to application of a corticosteroid cream or intralesional injections.
If lesions do not respond to local therapy or if skin disease is more generalized, some type of pharmacotherapy is required.
Systemic corticosteroids are usually used at least for the short term, but because of their many potential side effects, other agents should be considered for longer-term treatment.
Hydroxychloroquine is often the first steroid-sparing drug used.
Among the cytotoxic drugs, methotrexate seems to have a better response rate than other agents.
In some cases, derivatives of tetracycline have been helpful in mild disease.
Minocycline and doxycycline have been reported as useful for cutaneous sarcoidosis.
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