علاج داء الليشمانيات الجلدي البسيط سريريًا في المرضى مكتملي المناعة

DOI: 10.1093/cid/ciw670

We recommend that immunocompetent persons with skin lesions that are caused by infection with Leishmania species that are not associated with increased risk for ML, that are defined as clinically simple lesions (Table 1), and that are healing spontaneously may be observed without treatment if the patient concurs with this management.

Local therapy is preferred for treatment of Old World cutaneous leishmaniasis (OWCL) lesions defined as clinically simple (Table 1) and may be useful for localized NWCL caused by Leishmania species not associated with increased risk for ML.

Eschar(s) overlying ulcers should be debrided before administration of local therapy and any secondary infection managed to maximize treatment effect.

By 4–6 weeks after treatment, the lesion size should have decreased by >50%, ulcerative lesions should be reepithelializing, and no new lesions should be appearing.

Ulcerative lesions are generally fully reepithelialized and clinically healed by approximately 3 months after treatment.

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