داء كوشينغ الحاد: إدارة فرط الكورتيزول عندما يفشل العلاج الأحادي السريع في تطبيع مستويات الكورتيزول

References

DOI: 10.1016/S2213-8587(21)00235-7

1. For patients with severe disease, rapid normalization of cortisol is the most important goal.
2. Patients with severe CD who have potentially life-threatening metabolic, psychiatric, infectious, or cardiovascular/thromboembolic complications also may benefit from preoperative medical therapy in select cases.
3. For patients with severe hypercortisolism, combinations of steroidogenesis inhibitors may be necessary.
4. In patients with severe disease, the primary goal is to treat aggressively to normalize cortisol levels (or cortisol action if using mifepristone).