علاج فرط التنسج الكظري الخلقي الكلاسيكي (قصور 21-هيدروكسيلاز) في البالغين (العمر ≥18)

References

DOI: 10.1210/jc.2018-01865

• In adults with classic CAH, we recommend using daily HC and/or long-acting GCs plus mineralocorticoids (MCs), as clinically indicated.
• At or near completion of growth, long-acting GCs may be administered (Table 3), although HC remains the preferred treatment.
• Most nonhypertensive adults with classic CAH benefit from continued fludrocortisone treatment.
• For women, androstenedione and testosterone are good parameters of disease control (202), but additional tests should be considered in the context of menstrual irregularity and signs of androgen excess.
• In adults with congenital adrenal hyperplasia, we recommend that clinicians do not completely suppress endogenous adrenal steroid secretion to prevent adverse effects of over treatment.