متلازمة كوغان التي تستدعي العلاج بمثبطات المناعة الموفِّرة للستيرويد

References

• Prolonged steroid therapy should not be prescribed long-term at more than 5 to 7.5 mg/day of prednisone without considering steroid-sparing therapy.
• Maintenance therapy with an immunosuppressant/biologic therapy is justified in case of frequent steroid use, steroid dependence, or significant adverse effects.
• Conventional immunosuppressants (including methotrexate, azathioprine, mycophenolate mofetil, and cyclophosphamide) and/or targeted therapy (preferably infliximab, especially in case of cochleo-vestibular involvement) may be used.