علاج عدوى كلوستريديويدس ديفيسيلي غير الشديدة في الحلقة الأولى — عدد خلايا الدم البيضاء أقل من 15,000 خلية/مم³ والكرياتينين ≤ 1.5 ملغ/ديسيلتر

References

1. We recommend the following criteria, which are predictive of unfavorable outcomes, be used to classify severe C. difficile infection at the time of diagnosis: white blood cell (WBC) ≥15,000 cells/mm³ or serum creatinine >1.5 mg/dL.
2. We recommend that oral vancomycin 125 mg 4 times daily for 10 days be used to treat an initial episode of nonsevere CDI (strong recommendation, low quality of evidence).
3. We recommend that oral fidaxomicin 200 mg twice daily for 10 days be used for an initial episode of nonsevere CDI (strong recommendation, moderate quality of evidence).
4. Oral metronidazole 500 mg 3 times daily for 10 days may be considered for treatment of an initial nonsevere CDI in low-risk patients (strong recommendation/moderate quality of evidence).

DOI: 10.14309/ajg.0000000000001278