علاج عدوى المطثية العسيرة الخاطفة المدعومة بانخفاض ضغط الدم أو الصدمة أو انسداد الأمعاء أو الرتج السام

References

DOI: 10.1093/cid/ciab549

Definition of fulminant CDI is supported by: Hypotension or shock, ileus, megacolon.

The previous iteration of the guidelines also recommends vancomycin (500 mg 4 times daily orally or by nasogastric tube) rather than fidaxomicin for treatment of fulminant (previously known as severe, complicated) CDI.

Vancomycin 500 mg 4 times daily by mouth or by nasogastric tube. If ileus, consider adding rectal instillation of vancomycin. Intravenously administered metronidazole (500 mg every 8 hours) should be administered together with oral or rectal vancomycin, particularly if ileus is present.