ما هو علاج الخط الأول للشرى المزمن؟

References

DOI: 10.1111/all.70210

• We recommend a 2nd generation H1-antihistamine as first-line treatment for all types of urticaria.
• We recommend the use of a standard-dosed modern 2nd generation H1-antihistamines as the first-line symptomatic treatment for urticaria.
• Nonsedating 2nd generation H1-antihistamines, for example, should be used daily, to prevent the occurrence of wheals and angioedema, rather than on demand.
• The goal of treatment is to treat the disease until it is gone, as efficiently and as safely as possible, aiming at a continuous complete control (consistently UAS = 0/UCT = 16) and a normalization of quality of life.
• For updosing, also the time of onset needs to be considered, for example, for treatment with an antihistamine, further improvement cannot be expected after 1–2 weeks of treatment as receptor saturation is complete after 1 week.