يعالج هذا البروتوكول المرضى المصابين بقصور الكبد المزمن في سياق تليف الكبد الذين يعانون من نقص صوديوم الدم فرط الحجم — صوديوم المصل دون 130 مليمول/لتر — مصحوبًا بالاستسقاء والوذمة المحيطية.
The second, most common, is characterised by an expansion of the extracellular fluid volume, with ascites and oedema.
The use of hypertonic saline in the management of hypervolemic hyponatremia should be limited to the rare cases presenting with life threatening complications. It could also be considered in patients with severe hyponatremia who are expected to get LT within a few days. The correction of serum sodium concentration, once an attenuation of symptoms has been obtained, should be slow (≤8 mmol/L per day) to avoid irreversible neurological sequelae, such as osmotic demyelination (II-3;1).
DOI: 10.1016/j.jhep.2018.03.024
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