علاج ركود صفراء الحمل مع حكة وارتفاع الأحماض الصفراوية 40–99 µmol/L (الحالات المتوسطة الشدة)

References

DOI: 10.1111/1471-0528.17206

• The diagnosis of ICP should be considered in pregnant women who have itching in skin of normal appearance and raised peak random total bile acid concentration of 19 micromol/L or more.
• Moderate ICP: itching and raised peak bile acid concentrations 40–99 micromol/L.
• Consider topical emollients such as aqueous cream (with or without menthol added) to ameliorate skin symptoms.
• Consider antihistamine agents, such as chlorphenamine, particularly at night although the effectiveness of this treatment is uncertain in women with ICP.
• Consider planned birth at 38–39 weeks' gestation in women with moderate ICP with peak bile acids 40–99 micromol/L and no other risk factors; advise them that the overall risk of stillbirth is similar to the background risk until 38–39 weeks' gestation.