ورم البطانة العصبية داخل الجمجمة لدى البالغين من الدرجة الثانية/الثالثة وفق تصنيف منظمة الصحة العالمية: الإدارة بعد الجراحة عند عدم تحقيق الاستئصال الكلي الشامل

Key recommendations for the treatment of newly diagnosed intracranial WHO grades II and III ependymomas in adults.

In adults, radiotherapy is employed in patients with anaplastic ependymoma WHO grade III, and in case of incomplete resection of WHO grade II ependymoma.

Postoperative conformal radiotherapy with doses up to 60 Gy is recommended for patients with WHO grade III (anaplastic) ependymomas regardless of the extent of resection.

Postoperative conformal radiotherapy with doses of 54–59.4 Gy is recommended for patients with WHO grade II ependymomas following incomplete resection.

Craniospinal irradiation (CSI) of 36 Gy is recommended in case of CSF or spinal dissemination with a boost up to 45–54 Gy on focal lesions.

DOI: 10.1093/neuonc/nox166