ما هو العلاج الأول للساركويد القلبي؟

References

DOI: 10.1161/CIR.0000000000001240

• Corticosteroids are currently considered the first-line treatment for individuals with CS.
• Corticosteroids are initiated at doses of 30 to 40 mg/d of prednisone equivalent because there is no demonstrated benefit with higher starting doses.
• Initial combination therapy of corticosteroids with a steroid-sparing agent can be considered in severe clinical presentations or in individuals intolerant of moderate to high doses of corticosteroids.
• The response to treatment is measured in 2 ways: (1) improvement or resolution of the clinical presentation of arrhythmias, heart block, or HF and (2) reduction in the degree of active granulomatous inflammation in the myocardium.
• Although the optimal timing and frequency of surveillance FDG-PET scans during active treatment while immunosuppression therapy is being adjusted are not well established, 3- to 6-month intervals are typically used.