علاج متلازمة الكارسينويد في مرض القلب الكارسينويدي مع قلس الصمام الأيمن

References

DOI: 10.1111/jne.13146

• Carcinoid heart disease (CHD) is a rare and complex cardiac complication occurring in patients with advanced NETs and CS, usually manifesting mainly as right-sided heart valves regurgitation/stenosis (see Section A. d.) and eventually leading to right heart failure (RHF).
• The two main goals of management are aggressive reduction of hormonal secretion by the tumour and management of CHD and RHF, when present.
• In patients with symptomatic RHF, standard treatments, including loop/thiazide diuretics, aldosterone antagonist therapy and cautious fluid and salt restriction, can improve patient's symptoms but must be used judiciously to avoid a paradoxical worsening of symptoms because of a reduction in cardiac output.