التهاب القصيبات المسدة في متلقي زراعة الرئة مع الرفض الخلوي الحاد غير الأدنى

For lung transplant recipients who have non-minimal acute cellular rejection (Grade ≥A2) or lymphocytic bronchiolitis on transbronchial lung biopsy specimens, we suggest augmented immunosuppression with a course of systemic steroids to prevent the development of BOS (conditional recommendation, very low quality evidence).

A typical course of systemic corticosteroids used to augment immunosuppression in adult recipients is intravenous methylprednisolone 1000 mg daily for 3 days (many centres use 10–15 mg·kg⁻¹ per day for smaller patients).

DOI: 10.1183/09031936.00107514