علاج مرض بوين مع آفة جلدية أصغر من 2 سم في موقع منخفض الخطورة

References

DOI: 10.1093/bjd/ljac042

• SCC in situ that is small (< 2 cm) and at a low-risk site (such as the trunk and limbs) may be managed in primary care by a general practitioner who is capable of establishing a clinical diagnosis and initiating treatment options as per the guideline in the first instance.
• Lesions are considered large if > 2 cm and are considered high risk at periocular and digital (and penile) sites.
• Offer cryotherapy as a first-line treatment option to people with small (< 2 cm) SCC in situ lesions.
• Offer topical 5-fluorouracil (5%) monotherapy to people with SCC in situ, for small lesions (e.g. < 2 cm) in low-risk sites, and in those who will not or cannot undergo alternative treatments. Initiate a standard regimen of once- or twice-daily application for 3–4 weeks.
• Clearance (within 6 months).