علاج التسمم الوشيقي في التسمم الوشيقي الجرحي مع استخدام العقاقير بالحقن كعامل خطر

References

1. Risk factors for wound botulism include injection drug use (especially of black tar heroin) and for foodborne botulism include consumption of home-canned food.
2. Wound botulism is caused by clostridial colonization of an anaerobic wound, treatment of which is generally centered on debridement; treatment should address each patient's clinical situation.
3. Treatment involves supportive care, intubation and mechanical ventilation when necessary, and administration of equine-derived botulinum antitoxin.
4. When administered early in the course of illness (within 48 hours of symptom onset and ideally within 24 hours), botulinum antitoxin can stop the progression of paralysis and prevent respiratory compromise in certain patients.
5. If neurologic signs progress for >1 day after administration of one vial of BAT, consider diagnoses other than botulism.