علاج سرطان الخلايا القاعدية في الجلد في متلازمة غورلين مع أورام قاعدية خلوية متعددة

References

Gorlin syndrome is a rare, autosomal dominant familial cancer syndrome with a high degree of penetrance and variable expression.

Multiple BCCs in patients with Gorlin syndrome should be considered as laBCCs and treated accordingly.

In selected patients, treatment with Hedgehog inhibitors can be considered.

The oral dose is 150 mg/day for vismodegib and 200 mg/day for sonidegib.

DOI: 10.1016/j.ejca.2023.113254