علاج الورم الوعائي العصوي في الحمل

References

• In pregnancy, erythromycin or an alternative macrolide should be used as first-line therapy (AIII) rather than tetracyclines (such as doxycycline) due to toxicity profile; third-generation cephalosporins may have efficacy but are second line.
• Erythromycin treatment (or an alternative macrolide) should be used as first-line therapy (AIII) rather than tetracyclines (such as doxycycline) during pregnancy because of the increased risk of hepatotoxicity and the accumulation of tetracycline in fetal teeth and bones, resulting in dark, permanent staining of fetal teeth.
• For patients with positive or increasing antibody titers, but with clinical improvement, treatment should continue until at least a fourfold decrease in the antibody titers is documented (CIII).