علاج الصرع الجبهي الليلي السائد جسديًا: بروتوكول الخط الأول

References

DOI: 10.1007/s11910-013-0424-6

• Many and early reports documented carbamazepine as the drug of choice in NFLE/ADNFLE patients, and basic studies of ADNFLE mutations suggested that mutated nAChR receptors demonstrate an increased sensitivity to carbamazepine.
• According to the literature, about two thirds of NFLE/ADNFLE patients benefit from carbamazepine administration.
• This drug is usually given at low doses (200–1,000 mg at bedtime), abolishing seizures in ~20% of cases, and giving significant relief (at least 50% seizure reduction) in another 48%.