علاج التهاب اللسان الضموري في حالات جفاف الفم

Our previous studies found xerostomia in 79.0% of 176 AG patients and in 70.1% of 1064 AG patients.

AG patients with dry mouth can be treated by artificial salivas, continuous sips of water throughout the day, taking the sugarless candy to stimulate salivary secretion, using oral lubricant containing lactoperoxidase, lysozyme and lactoferrin (e.g., biotene mouth rinse and Oralbalance moisturizing gel), and systemic administration of sialagogue such as pilocarpine (Salagen, each tablet contains 7.5 mg pilocarpine hydrochloride, three to four times daily; a parasympathomimetic and muscarinic agonist with particular effect on muscarinic acetylcholine receptor M3) or cevimeline (Evoxac, 30 mg/cap, three times daily; a parasympathomimetic and muscarinic agonist with particular effect on M3 receptors).

Both pilocarpine and cevimeline are contraindicated in patients with asthma or narrow-angle glaucoma.