ينطبق هذا البروتوكول على المرضى الذين يعانون من التهاب الجلد التأتبي المتوسط أو الشديد والذين لم يحققوا سيطرة كافية على المرض — وتحديدًا تحسنًا بنسبة 50% في الشدة — مع إضافة الحمامات المخففة بالمبيض إلى العلاج الموضعي القياسي.
DOI: 10.1016/j.anai.2023.11.009
Recommendation 11: In patients with moderate-severe atopic dermatitis, the JTF panel suggests, in addition to topical therapy, dilute bleach baths over usual (no dilute bleach-based) baths (conditional recommendation, low-certainty evidence).
In patients with moderate-severe atopic dermatitis refractory, intolerant, or unable to use mid-potency topical treatment, the JTF panel suggests adding allergen immunotherapy to standard topical treatment over not adding (conditional recommendation, moderate-certainty evidence).
Based on a combination of clinician-reported AD severity (eg, SCORAD), AIT likely improved AD severity by 50% or more from baseline compared with no AIT (40% vs 26%), with similar estimates of effect for SCIT and SLIT.
Crude estimates of median time to effect were 5 (range 1-12) months.
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