ما هو علاج الخط الأول لداء الرشاشيات القصبي الرئوي التحسسي الحاد؟

References

• We recommend a low-to-moderate dose (0.5 mg·kg−1·day−1 for 2–4 weeks, tapered and completed over 4 months) of oral prednisolone (LoC: 78.1%) or oral itraconazole (LoC: 73.5%) for 4 months as the initial therapy for treating acute ABPA.
• We recommend oral itraconazole as the initial therapy where systemic glucocorticoids are contraindicated (LoC: 84.6%).
• After treatment initiation, patients should be monitored for response after 8–12 weeks using clinical symptoms, serum total IgE and chest radiographs.
• A good response is indicated by a major improvement in symptoms (Likert score or VAS ≥50%) and chest radiographs, along with at least a 20% reduction in serum total IgE.