علاج داء المثقبيات الأفريقية البشرية من النوع الغامبيانسي في المرضى الذين تبلغ أعمارهم ≥ 6 سنوات مع عدد كريات الدم البيضاء في السائل النخاعي أقل من 100/µL

References

• Fexinidazole is therefore the first-choice treatment in gambiense HAT patients aged ≥ 6 years and body weight ≥ 20 kg presenting without clinical features consistent with severe meningo-encephalitic HAT or presenting with < 100 WBC/µL in CSF.
• If the patient relapses after the above rescue treatments, then melarsoprol should be considered as a final treatment option due to its toxicity.
• Concomitant oral prednisolone may reduce the risk of adverse reactions, administered at 1 mg/kg per day (maximum dose 50 mg) for 9 days, tapering the dosage on days 10–12.