علاج داء الغدي الرحمي من الخط الأول: إدارة عسر الطمث والنزيف الحيضي الغزير

• Oral contraceptives, levonorgestrel-releasing intrauterine system, and dienogest should be used as first-line medical options for pain and heavy menstrual bleeding from adenomyosis (strong, moderate).
• Well-established non-hormonal options include non-steroidal anti-inflammatory drugs for management of dysmenorrhea and heavy menstrual bleeding, and tranexamic acid for heavy menstrual bleeding.
• Outcomes of interest include reduction in heavy menstrual bleeding, reduction in pelvic pain (dysmenorrhea, dyspareunia, chronic pelvic pain), and improvement in reproductive outcomes (fertility, miscarriage, adverse pregnancy outcomes).

DOI: 10.1016/j.jogc.2023.04.008