التهاب الجيوب الأنفية البكتيري الحاد غير المعقد مع فرط الحساسية المؤكد من النوع الأول للبنسلين — عند عدم نجاح الدوكسيسيكلين

References

DOI: 10.1002/ohn.1344

1. A clinician should diagnose ABRS when (a) symptoms or signs of acute rhinosinusitis (purulent nasal drainage accompanied by nasal obstruction, facial pain-pressure-fullness, or both) persist without evidence of improvement for at least 10 days beyond the onset of upper respiratory symptoms, or (b) symptoms or signs of acute rhinosinusitis worsen within 10 days after an initial improvement (double worsening).
2. When type-1 penicillin hypersensitivity is confirmed, doxycycline (100 mg or 200 mg PO bid) is recommended as an alternative agent for empiric antimicrobial therapy.
3. Respiratory fluoroquinolone (levofloxacin 500 mg or 750 mg PO od or moxifloxacin 400 mg PO od) is another alternative, but this antibiotic regimen should be reserved for those who have no alternative treatment options for reasons noted above.