علاج داء الكروانيات الرئوي الحاد مع أعراض خفيفة أو غير مُقعِدة (عرض سريري غير معقد، بدون قصور مناعي)

References

DOI: 10.1093/cid/ciw360

• We recommend patient education, close observation, and supportive measures such as reconditioning physical therapy for patients who appear to have mild or nondebilitating symptoms, or who have substantially improved or resolved their clinical illness by the time of diagnosis (strong, low).
• If treatment is begun in nonpregnant adults, the treatment should be an orally absorbed azole antifungal (eg, fluconazole) at a daily dose of ≥400 mg (strong, low).
• If treatment of early uncomplicated coccidioidal infection is instituted, the usual dose for adults is 400 mg daily. Some experts would recommend 800 mg daily.
• The duration is not certain, although many experts would recommend a treatment duration ranging from 3 to 6 months or longer, depending on the clinical response.
• Treatment can be discontinued when the patient's signs, symptoms, and inflammatory markers have resolved, and serologies and radiographs have stabilized.