علاج التهاب التامور الحاد عندما يكون الأسبرين ومضادات الالتهاب غير الستيرويدية موانع استخدام أو غير محتملة

References

DOI: 10.1093/eurheartj/ehaf192

• When aspirin and NSAIDs are contraindicated, or for specific indications, corticosteroids should be considered at low to moderate doses plus colchicine.
• For those with moderate to severe renal impairment, dose adjustment or use of corticosteroids is recommended.
• An important non-pharmacological concept is the restriction of physical activity beyond sedentary activities until symptom resolution and clinical remission with normalization of inflammatory markers.
• Low- to medium-dose corticosteroids should be considered for patients with pericarditis only in cases of contraindication/failure of aspirin/NSAIDs and colchicine, or when there is a specific indication to control symptoms and reduce recurrences.
• Clinical remission is defined as full regression of symptoms, as well as normalization of laboratory results (e.g. C-reactive protein, troponin levels) and investigations (ECG, evidence of PEff, CMR evidence of active inflammation).