علاج ابيضاض الدم الليمفاوي الحاد لدى المرضى فوق 55 عامًا

References

1. Many groups set an upper age limit for unmodified pediatric-based protocols at the age of 55 years.
2. A prephase therapy can be essential particularly for stabilization of the general condition.
3. As in protocols for younger patients, steroids and vincristine are the most important drugs in induction therapy.
4. One approach is the use of idarubicin in induction based on a potentially lower cardiac and hepatic toxicity.
5. Overall, it is advisable to start ASP in older patients later during consolidation.

DOI: 10.1182/blood.2023023568