علاج البثور الجلدية المعممة الحادة في الأطفال دون سن 18 بدون مشاركة جهازية

References

DOI: 10.1111/jdv.20232Digital

• In children
• In the most severe cases, that is, with systemic involvement (e.g. liver or kidney abnormalities and haemodynamic instability) or very acute skin lesions (erythroderma and disseminated pustules), a short systemic corticosteroid therapy with prednisone 0.5 mg/kg/day for a duration of 5–7 days may be considered.
• The suspected causal drug(s) must be stopped immediately and the pharmacovigilance department should be advised as soon as possible.
• All patients should be placed on bed rest until significant improvement and receive supportive care including mild soap substitutes baths or showers, moisturizing cream and oral or intravenous hydration according to the clinical status and biological changes.
• Even if the pustules tend to resolve spontaneously within a few days, with a characteristic pattern of punctate desquamation, most experts recommend the possible use of topical corticosteroids as specific treatment of AGEP.
• Grade III topical corticosteroids (e.g. betamethasone valerate and mometasone) can be used.
• As it is not a chronic disease, the most important is to use the quantity required for a complete healing of lesions.
• The fingertip unit (FTU) method can be proposed: 1 FTU, meaning 0.5g, covering a body surface area equivalent to two adult handprints.