علاج متلازمة فون ويلبراند المكتسبة في المرضى الخاضعين للجراحة الطفيفة

DOI: 10.5603/ahp.107038

• For patients undergoing minor surgery, desmopressin (DDAVP, 0.3 μg/kg i.v./s.c.) can be considered, with careful monitoring of vWF:Ag, FVIII:C, vWF:RCo/vWF:CB levels to guide repeat dosing due to its short effect duration.
• Antifibrinolytic agents (e.g., tranexamic acid 20–25 mg/kg q8–12h) are recommended as adjunctive therapy, particularly in surgical sites with high fibrinolytic activity, such as oral or gastrointestinal mucosa.