علاج متلازمة فون ويلبراند المكتسبة في أمراض المناعة الذاتية أو مع الأجسام المضادة الذاتية IgG المعادِلة

References

• In autoimmune diseases, glucocorticosteroids and other immunosuppressive drugs (cyclophosphamide, azathioprine, cyclosporine) are mainly used.
• Autoimmune diseases, other IgG inhibitors Neutralizing autoantibodies
• In patients who have developed alloantibodies to vWF, recombinant activated factor VIIA (rVIIa) is a valuable and highly effective drug.
• It is usually administered at a dose of 90 μg/kg (range, 40–150 μg/kg), in a cycle of approximately three doses.
• The use of rVIIa should be considered especially in patients who are refractory to standard therapy.