علاج حب الشباب الشائع الشديد بما في ذلك حب الشباب العقدي الشديد العنيد

References

DOI: 10.1016/j.jaad.2023.12.017

• Oral isotretinoin, or 13-cis-retinoic acid, is the only FDA-approved treatment for severe recalcitrant nodular acne vulgaris since 1982.
• Acne patients with psychosocial burden or scarring should be considered as having severe acne and to be candidates for isotretinoin.
• In a RCT of 925 patients comparing standard isotretinoin with lidose-isotretinoin, 81.0% of patients treated with standard isotretinoin experienced a 90% reduction in lesion count and 88.9% of patients treated with standard isotretinoin achieved treatment success after 20 weeks of treatment.