Aplastic anaemia presenting in patients over the age of 60 calls for careful individualisation of care. Older age brings a distinct set of clinical considerations that directly influence treatment selection and goals.
This protocol is specific to aplastic anaemia in elderly patients — those aged over 60 years. Treatment in this population is more complex than in younger patients due to the increased prevalence of comorbidity and the heightened risk of treatment toxicity. Quality of life assessment plays a particularly important role in guiding decisions in this age group.
For patients in this age group who are not candidates for, decline, or cannot tolerate more intensive interventions, care focuses on a structured supportive strategy directed at haematological stability and complication prevention.
The complete protocol — including specific interventions, sequencing, and individualised considerations — is available in the full structured regimen below.
DOI: 10.1111/bjh.19236
Treatment of elderly patients (>60 years) with AA is more complex than in younger patients due to comorbidity and treatment toxicity, and assessment of quality of life is especially relevant.
Patients unfit for, who decline or who are intolerant of IST should be offered the best supportive care (1C).
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