Certain patients with anterior uveitis show a clinically significant rise in intraocular pressure directly in response to steroid therapy — a pattern known as steroid responsiveness. This sub-population requires a distinct management approach that addresses intraocular inflammation while accounting for the steroid-induced pressure elevation.
The patient has anterior uveitis and develops raised intraocular pressure as a response to steroid treatment. The core challenge is controlling inflammation without further driving up intraocular pressure — a balance that standard steroid-centred regimens cannot achieve in this population.
DOI: 10.4103/0301-4738.58468
In steroid responders one should try and avoid steroid as far as possible and can use topical non-steroidal anti-inflammatory drugs (NSAIDs) like flubriprofen or weak steroids or steroids with least propensity to raise IOP such as rimexolone 1%.
When the patient is a steroid responder (i.e., increased IOP), concurrent treatment with a beta blocker is advised unless contraindicated.
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