Anterior uveitis
ICD-10 H20 · ICD-11 9A96

Treatment of Anterior Uveitis with Raised Intraocular Pressure in Response to Steroid Treatment

Certain patients with anterior uveitis show a clinically significant rise in intraocular pressure directly in response to steroid therapy — a pattern known as steroid responsiveness. This sub-population requires a distinct management approach that addresses intraocular inflammation while accounting for the steroid-induced pressure elevation.

The patient has anterior uveitis and develops raised intraocular pressure as a response to steroid treatment. The core challenge is controlling inflammation without further driving up intraocular pressure — a balance that standard steroid-centred regimens cannot achieve in this population.

In steroid responders, the protocol moves away from conventional steroid use where possible, favouring alternative topical anti-inflammatory options. Intraocular pressure management is incorporated concurrently, subject to any patient-specific contraindications. The full regimen details the specific agents, the conditions under which each applies, and the contraindication guidance.

Complete agent selection, sequencing, and clinical decision points are in the structured protocol.

References

DOI: 10.4103/0301-4738.58468

In steroid responders one should try and avoid steroid as far as possible and can use topical non-steroidal anti-inflammatory drugs (NSAIDs) like flubriprofen or weak steroids or steroids with least propensity to raise IOP such as rimexolone 1%.

When the patient is a steroid responder (i.e., increased IOP), concurrent treatment with a beta blocker is advised unless contraindicated.

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