Patients with Crohn's disease who develop symptomatic anorectal fistulas require a carefully structured clinical approach. This is a recognised and challenging complication of Crohn's disease, typically addressed through a combination of surgical and medical strategies.
Symptomatic anorectal fistula occurring in the setting of Crohn's disease — a complication warranting a structured, evidence-based management protocol tailored to this specific context.
The protocol for this scenario incorporates a cell-based regenerative approach delivered locally — the complete regimen, including patient selection criteria and full administration details, is available in the structured protocol below.
Anorectal fistula associated with Crohn's disease is typically managed with a combination of surgical and medical approaches.
Local administration of mesenchymal stem cells is a safe and effective treatment for selected patients with refractory anorectal fistulas in the setting of Crohn's disease.
DOI: 10.1097/DCR.0000000000002473
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