Treatment of External Anogenital Warts on the Penis, Groin, Scrotum, or Vulva
Clinical Scenario
This protocol covers external anogenital warts located on the penis, groin, scrotum, vulva, perineum, external anus, or perianus, in a person who is not pregnant.
Treatment Approach
Management includes both patient-applied topical therapies and provider-administered procedures — the full protocol specifies which options apply, how to choose among them, and what to monitor.
The complete regimen, selection criteria, and sequencing are available in the full structured protocol.
Treatment Goal
Resolution of anogenital warts.
Typically within 3 months of therapy
References
DOI: 10.15585/mmwr.rr7004a1
- Recommended Regimens for External Anogenital Warts (i.e., Penis, Groin, Scrotum, Vulva, Perineum, External Anus, or Perianus)
- Patient-applied: Imiquimod 3.75% or 5% cream
- Podofilox 0.5% solution or gel
- Sinecatechins 15% ointment
- Provider-administered: Cryotherapy with liquid nitrogen or cryoprobe
- Surgical removal by tangential scissor excision, tangential shave excision, curettage, laser, or electrosurgery
- Trichloroacetic acid (TCA) or bichloroacetic acid (BCA) 80%–90% solution
- Anogenital warts typically respond within 3 months of therapy.
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