First-Line Treatment of Ankle Osteoarthritis
Ankle osteoarthritis is a degenerative condition of the ankle joint. This protocol defines the first-line pharmacologic management approach for this condition.
Treatment approach
The first-line strategy involves a pharmacologic agent applied directly to the ankle joint — locally rather than systemically. The full protocol specifies the agent, its application guidance, and the complete clinical algorithm, none of which are shown here.
References
DOI: 10.1016/j.rdc.2022.03.009.
Topical NSAIDs were uniformly strongly recommended for knee OA by all guidelines and were strongly and conditionally recommended for hand OA by EULAR and ACR/AF, respectively, with the strength of recommendation influenced by practicality of using topical agents on finger joints.
Oral and topical NSAIDs are the pharmacologic agents most recommended for OA, though oral formulations should be avoided in those with contraindications and intolerances, and topical formulations are not appropriate for a deep joint such as the hip.
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