Hereditary angioedema (HAE) is an autosomal dominant disorder characterised by recurrent bouts of angioedema primarily affecting the extremities, gastrointestinal tract, and genitalia. A C4 complement level below 50% supports the diagnosis.
For severe attacks, a targeted replacement concentrate is the treatment of choice. The complete evidence-based regimen — including agent selection, clinical decision points, and sequencing — is available in the full structured protocol.
Hereditary angioedema (HAE) is an autosomal dominant disorder characterized by recurrent bouts of angioedema primarily affecting the extremities, gastrointestinal tract, and genitalia.
A C4 level below 50% suggests the diagnosis.
For patients with severe attacks, the treatment of choice is C1INH concentrate.
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