Treating Anemia When Iron Deficiency Is Ruled Out and Major Noncardiac Surgery Is Planned

Clinical Scenario

This protocol applies to patients with anemia in the context of chronic disease where iron deficiency has been excluded, and who are scheduled to undergo major noncardiac surgery — a recognised indication that warrants a structured perioperative approach.

Treatment Approach

Erythropoiesis-stimulating agent (ESA) therapy is indicated in this setting.

The full protocol — covering agent selection, perioperative timing, and monitoring — is available via the structured regimen below.

Instant Access to Structured Evidence-Based Regimens

References

DOI: 10.1016/j.kint.2025.06.006

Nevertheless, ESA therapy remains approved for a variety of indications, including patients who are anemic (and in whom iron deficiency has been ruled out) and scheduled for major noncardiac surgery (Table 4).

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