Satellite metastases and in-transit metastases are a recognized presentation of cutaneous amelanocytic melanoma. This protocol provides a structured, evidence-based management approach for patients in this specific clinical situation.
This protocol applies to patients presenting with satellite metastases or in-transit metastases of cutaneous melanoma. Whether the lesions are considered resectable is a central factor in shaping the management pathway.
For patients with resectable in-transit metastases, a surgical approach is part of the recommended management. The full protocol specifies the complete technical requirements and additional considerations that guide clinical decision-making.
DOI: 10.1016/j.annonc.2024.11.006
Patients with resectable ITMs should undergo complete excision with clear margins [IV, B].
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