Atrial fibrillation is the most common cardiac arrhythmia seen in AL amyloidosis. When cardiac involvement is present alongside AF, arrhythmia management requires a specific, evidence-guided first-line strategy tailored to this patient population.
AL amyloidosis with established cardiac involvement and concurrent atrial fibrillation — a combination that calls for careful, protocol-driven antiarrhythmic selection.
A specific first-line antiarrhythmic agent is recommended for this setting. The complete selection criteria, clinical algorithm, and supporting evidence are available in the full protocol.
DOI: 10.1200/OP.22.00396
With regard to cardiac arrythmias, atrial fibrillation is the most common, and usually amiodarone is the first-line agent in patients with AL amyloidosis with cardiac involvement.
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