Treatment of Adhesive Arachnoiditis When Potent Opioid Therapy Fails to Relieve Pain

Clinical Scenario

Adhesive arachnoiditis can produce severe, persistent pain. When potent opioid therapy fails to provide adequate pain relief, this protocol defines the structured next steps for escalating management.

Treatment Approach

The protocol considers interventional options — including a form of targeted delivery directly to the nervous system and an implanted neuromodulation device — as the structured response to medical failure of pain control.

The full criteria, sequencing, and clinical decision points are available in the complete protocol below.