Treatment of Acute Respiratory Failure in Immunosuppressed Patients

Early acute respiratory failure in immunosuppressed patients and in the post-operative setting requires a targeted respiratory support strategy, where the choice of intervention is directly shaped by the patient's immune status and clinical context.

Clinical scenario

This protocol applies to early acute respiratory failure occurring in immunosuppressed patients, and to acute respiratory failure arising in the post-operative setting. Immunosuppressed status is a key determinant of the recommended respiratory support approach in this population.

Approach

Noninvasive positive pressure ventilation (NPPV) is the guideline-recommended intervention for this clinical scenario — the complete selection criteria, application pathway, and full management protocol are available via the link below.

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References

The European Respiratory Society (ERS)/ATS guidelines recommend bilevel positive airway pressure (bilevel-PAP) for patients with acute exacerbation of COPD accompanied by acute hypercarbia, CPAP for cardiogenic pulmonary edema, and NPPV for post-operative setting and early ARF in immunosuppressed patients.

DOI: 10.1186/s40560-023-00658-3

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