This is a first-line management protocol for acute respiratory failure. It covers the primary ventilatory intervention strategy for this critical presentation, with specific parameters and decision criteria defined within the complete structured regimen.
The protocol involves invasive positive pressure ventilation (IPPV) as the central first-line intervention. The complete regimen — including specific ventilatory parameters, conditions for application, and the full clinical algorithm — is available in the structured protocol below.
DOI: 10.1186/s40560-023-00658-3
Regarding ARDS, IPPV has been the gold standard; however, HFNC and NPPV are weakly recommended as alternative options to initial management in JRS/JSICM/JSRCM-GL2021.
Limiting plateau pressure and high-level PEEP is recommended weakly to strongly in all guidelines, although the most recent Cochrane analysis did not find a survival benefit for high-level PEEP.
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