Acute respiratory failure
ICD-10 J96.0 · ICD-11 CB41.0Z

Treatment of Acute Respiratory Failure: First-Line Ventilatory Management

Acute respiratory failure demands prompt, structured intervention to restore adequate gas exchange and prevent further deterioration. First-line management centres on mechanical ventilatory support delivered according to evidence-based protocols.

First-line approach

The current evidence supports invasive positive pressure ventilation as the primary intervention — applied alongside a lung-protective ventilation strategy. The complete protocol specifies the full clinical decision pathway, parameters, and criteria for escalation.

Instant Access to Structured Evidence-Based Regimens

References

DOI: 10.1186/s40560-023-00658-3

Low tidal volume ventilation is weakly recommended for ARF in SSCG2021 and SRLF-GL2019, and strongly recommended for ARDS in JRS/JSICM/JSRCM-GL2021, SSCG2021, SRLF-GL2019 and FICM/ICS-GL2018.

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