Treatment of Acute Pyelonephritis Requiring Hospitalisation

This protocol covers patients with acute pyelonephritis whose condition requires hospital admission. Inpatient management allows initiation of intravenous therapy and close clinical monitoring during the acute phase.

Initial management centres on empirical parenteral antimicrobial therapy. Agent selection, dosing considerations, and the criteria for switching to an oral regimen are set out in the full structured protocol …

The target endpoint is clinical improvement together with the ability to tolerate oral fluids — at which point the transition from parenteral to oral antimicrobial therapy is made.