This protocol applies to immunocompetent patients — adults and children with no immunocompromising condition — who present with mild acute pulmonary histoplasmosis.
Mild acute pulmonary histoplasmosis is characterised by mild symptoms — such as cough, fever, dyspnea, or chest discomfort — that do not interfere with normal daily activities.
Current evidence-based guidance specifically addresses the role of antifungal treatment in this population, with a conditional recommendation based on available evidence. Access the full structured protocol for the complete recommendation and management criteria.
DOI: 10.1093/cid/ciaf256
In immunocompetent adults and children presenting with mild acute pulmonary histoplasmosis, the panel suggests against routinely providing antifungal treatment (conditional recommendation, very low certainty of evidence).
Mild acute pulmonary histoplasmosis — mild symptoms (eg, cough, fever, dyspnea, chest discomfort) that do not interfere with normal activities.
View source ↗