Treatment of Acute Pulmonary Blastomycosis in a Newborn with Evidence of Blastomycosis Infection

Acute pulmonary blastomycosis in a newborn is a serious clinical scenario requiring prompt, targeted management. When a neonate presents with evidence of blastomycosis infection, a specific antifungal treatment approach is recommended.

Clinical Scenario A newborn with confirmed or suspected evidence of blastomycosis infection. This population requires a treatment strategy distinct from that used in older children or adults.
Treatment Approach When the newborn shows evidence of infection, antifungal therapy with Amphotericin B deoxycholate is recommended. Complete dosing, administration details, and the full clinical regimen are available in the structured protocol below.

References

DOI: 10.1086/588300

If the newborn shows evidence of infection, treatment is recommended with AmB deoxycholate, 1.0 mg/kg per day (A-III).

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